Genome-wide host responses against infectious laryngotracheitis virus vaccine infection in chicken embryo lung cells

Replication Kinetic of Infectious Laryngotracheitis Virus in Embryonic Chicken Neural Stem Cell

Background and Aims: Infectious laryngotracheitis virus (ILTV) infection causes a highly contagious respiratory disease in poultry leads to significant economic losses in the poultry industry. The genomic and antigenic characteristics between virulent and vaccine strains of ILTV are very similar. The ability of embryonated chicken neural stem (CNS) cell for differential diagnosis of ILTV strain...

Chicken infectious anaemia virus infection among broiler chicken flocks in Iran

Chicken infectious anaemia is a viral disease in young chickens which characterized by aplastic anaemia and immunosuppression. Between January 2004 and July 2005, an unusual hemorrhage in subcutaneous and intramuscular tissues of broiler chickens at slaughter houses of Mashhad, Isfahan and Tehran provinces were occurred. Postmortem examination revealed severe hemorrhages in the wings and muscle...

Genome-Wide Gene Expression Analysis Identifies the Proto-oncogene Tyrosine-Protein Kinase Src as a Crucial Virulence Determinant of Infectious Laryngotracheitis Virus in Chicken Cells

UNLABELLED Given the side effects of vaccination against infectious laryngotracheitis (ILT), novel strategies for ILT control and therapy are urgently needed. The modulation of host-virus interactions is a promising strategy to combat the virus; however, the interactions between the host and avian ILT herpesvirus (ILTV) are unclear. Using genome-wide transcriptome studies in combination with a ...

Studies on the immunogenic proprties of a Live Infectious Laryngotracheitis virus vaccine

Molecular biology of avian infectious laryngotracheitis virus.

Infectious laryngotracheitis virus (ILTV) is an alphaherpesvirus that causes an economically important chicken disease, which results in delayed growth, reduced egg production, and also frequently in death of the animals. After acute infection of the upper respiratory tract, the virus can establish latency in the central nervous system, and subsequent reactivations can lead to infection of naiv...